Discover the power of Prehab™
Discover the power of Prehab™
The world’s first Prehab™ platform
Introducing BLOOM⁴³
Prehabilitation (Prehab™) is like rehabilitation in reverse - optimizing your mental and physical health in preparation for surgery.
The BLOOM⁴³ Prehab™ Platform combines an award-winning medical device for preconditioning of the surgical site, and a smartphone app designed to support, educate and prepare patients.
Our mission is to empower patients to actively and holistically prehabilitate before breast surgery, in order to minimize complications and improve outcomes.
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1. Prehabilitate with the BLOOM⁴³ app
The BLOOM43 app is a free, comprehensive resource intended for use by anyone undergoing breast surgery, or their support network.
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Follow an 8-week pre- and post-surgery program with expert insights to guide you before, during, and after your procedure.
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Explore a vast library of evidence-based articles and videos to help you navigate your surgical journey with confidence.
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Be part of a community where stories are shared, encouragement is abundant, and no one feels alone.
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Monitor your recovery, track and learn about symptoms, and securely upload clinical photographs, documents and appointment details all in one place.
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Confirm your role as a member of a patient’s support network to access tailored content that empowers you to understand and help them.
2. Precondition with the BLOOM⁴³ medical device
The BLOOM⁴³ device delivers ultra-precise thermal supraphysiological preconditioning™ to boost blood flow and prime the skin before breast surgery. Previous clinical trials have shown that this technique can reduce the risk of wound healing complications, such as skin necrosis. Preventing complications leads to safer recoveries for patients and more efficient care for providers. Preventing complications leads to safer recoveries for patients and more efficient care for providers.
Available for purchase on the BLOOM⁴³ app
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BLOOM⁴³ is a Class II, 510(k)-exempt medical device that meets IEC 60601-1 and EMC requirements.
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Our quality management system meets international standards for manufacturing safe and reliable medical devices.
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Supraphysiological preconditioning™ has been shown to be effective in two proof-of-concept clinical trials.
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Worn inside a bra for just three hours on the night before surgery, the BLOOM⁴³ device works by gently heating the breast skin to 43°C (108°F).
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Designed to be lightweight, comfortable, and portable, the BLOOM⁴³ device enables normal daily activities to continue without disruption.
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Built to the highest standards of safety, the BLOOM⁴³ device is easy to use within the comfort of your own home
What patients are saying
What healthcare professionals are saying
“Congratulations on your success in bringing this idea forward. I am all for anything that would help prevent mastectomy flap necrosis.”
Dr Dennis Hammond MD, Partners in Plastic Surgery of West Michigan
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“We’re truly excited to be collaborating with Plexāā on the BLOOM⁴³ platform. It aligns perfectly with our mission to support patients through every step of their surgical journey — both physically and emotionally. The combination of evidence-based guidance and digital innovation is exactly what the future of patient care looks like.”
— Dr David Boudreault, MD, FACS
ILLUMINATE PLASTIC SURGERY
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“The team is excited about all the support that BLOOM⁴³ has to offer us. I believe that this is important new technology that will improve patient satisfaction and patient safety in a meaningful way.”
— Dr Daniel Mills, MD, FACS
AESTHETIC PLASTIC SURGICAL INSTITUTE
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"Healing well after a mastectomy is such a big concern for so many people, and I know it was a huge one for me! I did everything I could to get my body ready in terms of exercising and eating well, but was also grateful to have extra help with the use of BLOOM⁴³."
— Dr Anne Peled, MD
PLASTIC SURGEON & BREAST CANCER SURVIVOR
Evidence-based
The BLOOM⁴³ device delivers ultra-precise supraphysiological preconditioning™ to boost blood flow and prime the skin, helping lower the risk of post-op complications.
Using a sensor-controlled, patented intermittent thermal algorithm, BLOOM⁴³ stimulates the release of protective heat shock proteins (HSPs), including HSP-32.
This induces the local release of carbon monoxide, which is a potent vasodilator that enhances tissue blood flow.
Better blood flow means better healing.
*Sources: “Local Heat Preconditioning in Skin Sparing Mastectomy: A Pilot Study”, Mehta S, Rolph R, Cornelius V et al., 2013; “A Randomised Controlled Feasibility Trial to Evaluate Local Heat Preconditioning on Wound Healing After Reconstructive Breast Surgery: The preHEAT Trial.”, Mehta S, Cro SC, Coomber B et al., 2019.**Source: Mehta et al, 2019.

